Lab members

Shabana Khan

Shabana Khan
Postdocs

shabana.khan@kcl.ac.uk

Bio

I completed my undergraduate degree in Biomedical Sciences from University College London (UCL) in 2010, specialising in the neurosciences and developmental biology, during which I undertook a research project in Prof John Parnavelas’s group on cellular mechanisms of neuronal migration in the developing cortex. I graduated with an MSc in Clinical Neurosciences in 2011 from UCL’s Queen Square Institute of Neurology. I was awarded a 4-year MRC Studentship to pursue my PhD in Developmental Neurobiology at the Francis Crick Institute in Dr Siew-Lan Ang’s lab where I studied the molecular heterogeneity of midbrain dopamine neurons. My PhD work uncovered the role of NeuroD family of bHLH transcription factors in the survival of a novel subset of midbrain dopaminergic neurons projecting to the lateral septum. In 2017, I joined the Synaptic Plasticity and Repair group at Imperial College London & MRC LMS, with Dr Vincenzo De Paola on a MRC postdoctoral fellowship. I investigated the dynamics of injured human cortical synaptic networks and developed new in vivo models of human cortical axon regeneration, degeneration and Down syndrome using transplanted donor-derived cells, intravital longitudinal 2-Photon microscopy, laser microsurgery, calcium imaging and non-invasive neurostimulation methods. My research interest in the roles of neural activity in the assembly, dysfunction, repair and enhancement of cortical circuits have led me to join Prof Beatriz Rico’s group in 2021 at King’s College London’s Centre for Developmental Neurobiology & MRC CNDD. I will be working on an ERC-funded project to investigate the effects of enhanced early sensory experience in functional remodelling and plasticity of inhibitory cortical networks.

 

Outside of the lab, I enjoy travelling, swimming, photography, SciArt, reading fiction as well as Japanese and S.Korean cinema.

contact_mail

Contact us at beatriz.rico@kcl.ac.uk or give us a call +44 20 78486552

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